Murine coagulation factor VIII is synthesized in endothelial cells

The primary cellular source of factor VIII (FVIII) biosynthesis is controversial, with contradictory evidence supporting an endothelial or hepatocyte origin. LMAN1 is a cargo receptor in the early secretory pathway that is responsible for the efficient secretion of factor V (FV) and FVIII to the pla...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Everett, Lesley A., Cleuren, Audrey C. A., Khoriaty, Rami N., Ginsburg, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2014
Pynciau:
Plenary Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055920/
https://ncbi.nlm.nih.gov/pubmed/24719406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554501
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