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Murine coagulation factor VIII is synthesized in endothelial cells
The primary cellular source of factor VIII (FVIII) biosynthesis is controversial, with contradictory evidence supporting an endothelial or hepatocyte origin. LMAN1 is a cargo receptor in the early secretory pathway that is responsible for the efficient secretion of factor V (FV) and FVIII to the pla...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055920/ https://ncbi.nlm.nih.gov/pubmed/24719406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554501 |
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