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Murine coagulation factor VIII is synthesized in endothelial cells
The primary cellular source of factor VIII (FVIII) biosynthesis is controversial, with contradictory evidence supporting an endothelial or hepatocyte origin. LMAN1 is a cargo receptor in the early secretory pathway that is responsible for the efficient secretion of factor V (FV) and FVIII to the pla...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055920/ https://ncbi.nlm.nih.gov/pubmed/24719406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554501 |
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