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Murine coagulation factor VIII is synthesized in endothelial cells

The primary cellular source of factor VIII (FVIII) biosynthesis is controversial, with contradictory evidence supporting an endothelial or hepatocyte origin. LMAN1 is a cargo receptor in the early secretory pathway that is responsible for the efficient secretion of factor V (FV) and FVIII to the pla...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Everett, Lesley A., Cleuren, Audrey C. A., Khoriaty, Rami N., Ginsburg, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055920/
https://ncbi.nlm.nih.gov/pubmed/24719406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554501
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