TOC1: A valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy

All tauopathies result in various forms of cognitive decline and neuronal loss. Although in some diseases, tau mutations appear to cause neurodegeneration, the toxic “form” of tau remains elusive. Tau is the major protein found within neurofibrillary tangles (NFTs) and therefore it seemed rational t...

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Bibliografiske detaljer
Main Authors: Ward, Sarah M., Himmelstein, Diana S., Ren, Yan, Fu, Yifan, Yu, Xiao-Wen, Roberts, Kaleigh, Binder, Lester I., Sahara, Naruhiko
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055868/
https://ncbi.nlm.nih.gov/pubmed/24631720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.03.002
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