Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

BACKGROUND: Cross-breeding of transgenic mice is commonly used to assess gene-gene interactions, particularly in the context of disease. Strain background changes can influence the phenotype of mouse models and can confound crossbreeding studies. We sought to determine if changing the strain backgro...

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Bibliografiske detaljer
Main Authors:	Bailey, Rachel M, Howard, John, Knight, Joshua, Sahara, Naruhiko, Dickson, Dennis W, Lewis, Jada
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2014
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3896770/ https://ncbi.nlm.nih.gov/pubmed/24428919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-8
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Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

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