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Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model
BACKGROUND: Cross-breeding of transgenic mice is commonly used to assess gene-gene interactions, particularly in the context of disease. Strain background changes can influence the phenotype of mouse models and can confound crossbreeding studies. We sought to determine if changing the strain backgro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896770/ https://ncbi.nlm.nih.gov/pubmed/24428919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-8 |
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