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TOC1: A valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy

All tauopathies result in various forms of cognitive decline and neuronal loss. Although in some diseases, tau mutations appear to cause neurodegeneration, the toxic “form” of tau remains elusive. Tau is the major protein found within neurofibrillary tangles (NFTs) and therefore it seemed rational t...

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Hlavní autoři: Ward, Sarah M., Himmelstein, Diana S., Ren, Yan, Fu, Yifan, Yu, Xiao-Wen, Roberts, Kaleigh, Binder, Lester I., Sahara, Naruhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055868/
https://ncbi.nlm.nih.gov/pubmed/24631720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.03.002
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