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Structural abnormalities in the cortex of the rTg4510 mouse model of tauopathy: a light and electron microscopy study
rTg4510 transgenic (TG) mice overexpress mutant (P301L) human tau protein. We have compared the dorsal premotor cortex of TG mice versus non-transgenic (NT) mice at 4, 9, and 13 months of age, using light (LM) and electron microscopy (EM). LM assessment shows that cortical thickness in TG mice is re...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748379/ https://ncbi.nlm.nih.gov/pubmed/21152933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-010-0295-4 |
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