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Herpes Simplex Virus Protein Kinases US3 and UL13 Modulate VP11/12 Phosphorylation, Virion Packaging, and Phosphatidylinositol 3-Kinase/Akt Signaling Activity

The phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway plays key roles in diverse cellular activities and promotes cell growth and survival. It is therefore unsurprising that most viruses modify this pathway in order to facilitate their replication and spread. Previous work has suggested tha...

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Detalhes bibliográficos
Main Authors: Eaton, Heather E., Saffran, Holly A., Wu, Frederick W., Quach, Kevin, Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054420/
https://ncbi.nlm.nih.gov/pubmed/24741093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00712-14
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