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Herpes Simplex Virus Requires VP11/12 To Activate Src Family Kinase-Phosphoinositide 3-Kinase-Akt Signaling

We previously showed that the herpes simplex virus 1 (HSV-1) tegument protein VP11/12 activates the lymphocyte-specific Src family kinase (SFK) Lck and is tyrosine phosphorylated in an Lck-dependent manner during T cell infection. We now extend these findings to show that ectopic expression of Lck i...

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Detalhes bibliográficos
Main Authors: Wagner, Melany J., Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067919/
https://ncbi.nlm.nih.gov/pubmed/21228233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01877-10
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