CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies

Approaches to prevent human immunodeficiency virus (HIV-1) transmission are urgently needed. Difficulties in eliciting antibodies that bind conserved epitopes exposed on the unliganded conformation of the HIV-1 envelope glycoprotein (Env) trimer represent barriers to vaccine development. During HIV-...

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Main Authors: Madani, Navid, Princiotto, Amy M., Schön, Arne, LaLonde, Judith, Feng, Yu, Freire, Ernesto, Park, Jongwoo, Courter, Joel R., Jones, David M., Robinson, James, Liao, Hua-Xin, Moody, M. Anthony, Permar, Sallie, Haynes, Barton, Smith, Amos B., Wyatt, Richard, Sodroski, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054336/
https://ncbi.nlm.nih.gov/pubmed/24696475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00540-14
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