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Synthesis and characterization of a high-affinity α(v)β(6)-specific ligand for in vitro and in vivo applications

The α(v)β(6) integrin is an attractive therapeutic target for several cancers due to its role in metastasis and its negligible expression in normal tissues. We previously identified a peptide from a phage-displayed peptide library that binds specifically to α(v)β(6). The tetrameric version of the pe...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Li, Shunzi, McGuire, Michael J., Lin, Mai, Liu, Ying-Horng, Oyama, Tsukasa, Sun, Xiankai, Brown, Kathlynn C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053473/
https://ncbi.nlm.nih.gov/pubmed/19435868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1098
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