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Synthesis and Biological Evaluation of a Peptide Paclitaxel Conjugate Which Targets the Integrin α(v)β(6)

The integrin α(v)β(6) is an emergent biomarker for non-small cell lung cancer (NSCLC) as well as other carcinomas. We previously developed a tetrameric peptide, referred to as H2009.1, which binds α(v)β(6) and displays minimal affinity for other RGD-binding integrins. Here we report the use of this...

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Detalhes bibliográficos
Main Authors: Li, Shunzi, Gray, Bethany Powell, McGuire, Michael J, Brown, Kathlynn C
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195361/
https://ncbi.nlm.nih.gov/pubmed/21868241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.07.046
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