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From Phage Display to Nanoparticle Delivery: Functionalizing Liposomes with Multivalent Peptides Improves Targeting to a Cancer Biomarker

Phage display is commonly used to isolate peptides that bind to a desired cell type. While chemical synthesis of selected peptides often results in ligands with low affinity, a multivalent tetrameric presentation of the peptides dramatically improves affinity. One of the primary uses of these peptid...

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Detalles Bibliográficos
Main Authors: Gray, Bethany Powell, Li, Shunzi, Brown, Kathlynn C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561762/
https://ncbi.nlm.nih.gov/pubmed/23186007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300498d
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