Dimerization of a Phage-Display Selected Peptide for Imaging of α(v)β(6)- Integrin: Two Approaches to the Multivalent Effect

The integrin α(v)β(6) is an emerging biomarker for non-small cell lung cancer (NSCLC). An α(v)β(6)-binding peptide was previously selected from a phage-displayed peptide library. Here, we utilize a multivalent design to develop a peptidic probe for positron emission tomography (PET) imaging of α(v)β...

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Bibliografiska uppgifter
Huvudupphovsmän: Singh, Ajay N., McGuire, Michael J., Li, Shunzi, Hao, Guiyang, Kumar, Amit, Sun, Xiankai, Brown, Kathlynn C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038756/
https://ncbi.nlm.nih.gov/pubmed/24883124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.7811
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