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Peptide-Targeted Polyglutamic Acid Doxorubicin Conjugates for the Treatment of α(v)β(6)-Positive Cancers

Most chemotherapeutics exert their effects on tumor cells as well as their healthy counterparts, resulting in dose limiting side effects. Cell-specific delivery of therapeutics can increase the therapeutic window for treatment by maintaining the therapeutic efficacy while decreasing the untoward sid...

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Detalhes bibliográficos
Main Authors: Guan, Huili, McGuire, Michael J., Li, Shunzi, Brown, Kathlynn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053474/
https://ncbi.nlm.nih.gov/pubmed/18710273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800154f
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