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Synthesis and characterization of a high-affinity α(v)β(6)-specific ligand for in vitro and in vivo applications

The α(v)β(6) integrin is an attractive therapeutic target for several cancers due to its role in metastasis and its negligible expression in normal tissues. We previously identified a peptide from a phage-displayed peptide library that binds specifically to α(v)β(6). The tetrameric version of the pe...

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Bibliografiske detaljer
Main Authors: Li, Shunzi, McGuire, Michael J., Lin, Mai, Liu, Ying-Horng, Oyama, Tsukasa, Sun, Xiankai, Brown, Kathlynn C.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053473/
https://ncbi.nlm.nih.gov/pubmed/19435868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1098
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