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Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress
Proteasome is central to proteostasis maintenance, as it degrades both normal and damaged proteins. Herein, we undertook a detailed analysis of proteasome regulation in the in vivo setting of Drosophila melanogaster. We report that a major hallmark of somatic tissues of aging flies is the gradual ac...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050428/ https://ncbi.nlm.nih.gov/pubmed/23457214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-221408 |
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