Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging

Lignende værker

• Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress
  af: Tsakiri, Eleni N., et al.
  Udgivet: (2013)
• Molecular responses to therapeutic proteasome inhibitors in multiple myeloma patients are donor-, cell type- and drug-dependent
  af: Papanagnou, Eleni-Dimitra, et al.
  Udgivet: (2018)
• Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy
  af: Tsakiri, Eleni N., et al.
  Udgivet: (2019)
• Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation
  af: Tsakiri, Eleni N., et al.
  Udgivet: (2018)
• Redox Status and Proteostasis in Ageing and Disease
  af: Rizzi, Federica, et al.
  Udgivet: (2016)