RASSF6 promotes p21(Cip1/Waf1)-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is a highly aggressive and common pathological subtype of renal cancer. This cancer is characterized by biallelic inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene, which leads to the accumulation of hypoxia-inducible factors (HIFs). Although t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liang, Ying-Ying, Zheng, Li-Sheng, Wu, Yuan-Zhong, Peng, Li-Xia, Cao, Yun, Cao, Xue, Xie, Ping, Huang, Bi-Jun, Qian, Chao-Nan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050141/
https://ncbi.nlm.nih.gov/pubmed/24626183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28416
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