RASSF6 promotes p21(Cip1/Waf1)-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is a highly aggressive and common pathological subtype of renal cancer. This cancer is characterized by biallelic inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene, which leads to the accumulation of hypoxia-inducible factors (HIFs). Although t...

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Detaylı Bibliyografya
Asıl Yazarlar: Liang, Ying-Ying, Zheng, Li-Sheng, Wu, Yuan-Zhong, Peng, Li-Xia, Cao, Yun, Cao, Xue, Xie, Ping, Huang, Bi-Jun, Qian, Chao-Nan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2014
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050141/
https://ncbi.nlm.nih.gov/pubmed/24626183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28416
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