Interferon Regulatory Factor 1 (IRF-1) Induces p21(WAF1/CIP1) Dependent Cell Cycle Arrest and p21(WAF1/CIP1) Independent Modulation of Survivin in Cancer Cells

We have shown that the ectopic expression of Interferon Regulatory Factor (IRF-1) results in human cancer cell death accompanied by the down-regulation of the Inhibitor of Apoptosis Protein (IAP) survivin and the induction of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1). In this report, we i...

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Main Authors: Armstrong, Michaele J., Stang, Michael T., Liu, Ye, Gao, Jinbo, Ren, Baoguo, Zuckerbraun, Brian S., Mahidhara, Raja S., Xing, Quanhua, Pizzoferrato, Eva, Yim, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304016/
https://ncbi.nlm.nih.gov/pubmed/22200613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.12.027
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