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Characterization of a panel of novel anti-p21Waf1/Cip1 monoclonal antibodies and immunochemical analysis of p21Waf1/Cip1 expression in normal human tissues.

As a universal inhibitor of cyclin-dependent kinases and one of the target genes of the tumor suppresser p53, p21Waf1/Cip1 can act as a tumor suppresser through its ability to control cell cycle progression. To study the function of p21Waf1/Cip1 protein and to investigate its tissue distribution, a...

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Bibliographic Details
Main Authors: Fredersdorf, S., Milne, A. W., Hall, P. A., Lu, X.
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861740/
https://ncbi.nlm.nih.gov/pubmed/8774137
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