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Epigenetic Regulation of p21(cip1/waf1) in Human Cancer

p21(cip1/waf1) is a central regulator of cell cycle control and survival. While mutations are rare, it is commonly dysregulated in several human cancers due to epigenetic mechanisms influencing its transcriptional control. These mechanisms include promoter hypermethylation as well as additional path...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ocker, Matthias, Al Bitar, Samar, Monteiro, Ana Carolina, Gali-Muhtasib, Hala, Schneider-Stock, Regine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769618/
https://ncbi.nlm.nih.gov/pubmed/31514410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091343
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