The Role of the Cyclin Dependent Kinase Inhibitor p21(cip1/waf1) in Targeting Cancer: Molecular Mechanisms and Novel Therapeutics

Por Al Bitar, Samar, Gali-Muhtasib, Hala
Publicado no Cancers (Basel) (2019)

A Journey Under the Sea: The Quest for Marine Anti-Cancer Alkaloids

Por Tohme, Rita, Darwiche, Nadine, Gali-Muhtasib, Hala
Publicado no Molecules (2011)

Overview of Major Classes of Plant-Derived Anticancer Drugs

Por Amin, Amr, Gali-Muhtasib, Hala, Ocker, Matthias, Schneider-Stock, Regine
Publicado em 2009

Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells

Por Itani, Wafica, Geara, Fady, Haykal, Joelle, Haddadin, Makhluf, Gali-Muhtasib, Hala
Publicado em 2007

Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21

Por El-Khatib, Mona, Geara, Fady, Haddadin, Makhluf J, Gali-Muhtasib, Hala
Publicado em 2010

Emerging Cytotoxic Alkaloids in the Battle against Cancer: Overview of Molecular Mechanisms

Por Habli, Zeina, Toumieh, Georgio, Fatfat, Maamoun, Rahal, Omar Nasser, Gali-Muhtasib, Hala
Publicado no Molecules (2017)

The radiosensitizer 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide induces DNA damage in EMT-6 mammary carcinoma cells

Por Haykal, Joelle, Geara, Fady, Haddadin, Makhluf J, Smith, Colin A, Gali-Muhtasib, Hala
Publicado em 2009

Epigenetic Regulation of p21(cip1/waf1) in Human Cancer

Por Ocker, Matthias, Al Bitar, Samar, Monteiro, Ana Carolina, Gali-Muhtasib, Hala, Schneider-Stock, Regine
Publicado no Cancers (Basel) (2019)

The Cytotoxic and Apoptotic Effects of the Brown Algae Colpomenia sinuosa are Mediated by the Generation of Reactive Oxygen Species

Por Al Monla, Reem, Dassouki, Zeina, Kouzayha, Achraf, Salma, Yahya, Gali-Muhtasib, Hala, Mawlawi, Hiba
Publicado no Molecules (2020)

Differential Growth Inhibitory Effects of Highly Oxygenated Guaianolides Isolated from the Middle Eastern Indigenous Plant Achillea falcata in HCT-116 Colorectal Cancer Cells

Por Tohme, Rita, Aaraj, Lamis Al, Ghaddar, Tarek, Gali-Muhtasib, Hala, Saliba, Najat A., Darwiche, Nadine
Publicado no Molecules (2013)

Novel 2-(5-Imino-5H-isoquinolones[3,4-b]quinoxalin-7-ylmethyl)-benzonitrile (DIQ3) and Other Related Derivatives Targeting Colon Cancer Cells: Syntheses and in Vitro Models

Por Monzer, Alissar, Jabotian, Nayri, Ballout, Farah, Zhu, Jie S., Kurth, Mark J., Haddadin, Makhluf J., Gali-Muhtasib, Hala
Publicado no ACS Omega (2019)

The quinoxaline di-N-oxide DCQ blocks breast cancer metastasis in vitro and in vivo by targeting the hypoxia inducible factor-1 pathway

Por Ghattass, Khaled, El-Sitt, Sally, Zibara, Kazem, Rayes, Saide, Haddadin, Makhluf J, El-Sabban, Marwan, Gali-Muhtasib, Hala
Publicado em 2014

Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer

Por El-Baba, Chirine, Mahadevan, Vijayalakshmi, Fahlbusch, Fabian B, S, Suma Mohan, Rau, Tilman T, Gali-Muhtasib, Hala, Schneider-Stock, Regine
Publicado em 2014

Impact of protein binding on the analytical detectability and anticancer activity of thymoquinone

Por El-Najjar, Nahed, Ketola, Raimo A., Nissilä, Teemu, Mauriala, Timo, Antopolsky, Maxim, Jänis, Janne, Gali-Muhtasib, Hala, Urtti, Arto, Vuorela, Heikki
Publicado em 2011

Copper chelation selectively kills colon cancer cells through redox cycling and generation of reactive oxygen species

Por Fatfat, Maamoun, Merhi, Raghida Abou, Rahal, Omar, Stoyanovsky, Detcho A, Zaki, Angela, Haidar, Hazar, Kagan, Valerian E, Gali-Muhtasib, Hala, Machaca, Khaled
Publicado no BMC Cancer (2014)

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells

Por Ballout, Farah, Monzer, Alissar, Fatfat, Maamoun, Ouweini, Hala El, Jaffa, Miran A., Abdel-Samad, Rana, Darwiche, Nadine, Abou-Kheir, Wassim, Gali-Muhtasib, Hala
Publicado no Oncotarget (2020)

Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G(2) checkpoint arrest

Por Poehlmann, Angela, Habold, Caroline, Walluscheck, Diana, Reissig, Kathrin, Bajbouj, Khuloud, Ullrich, Oliver, Hartig, Roland, Gali-Muhtasib, Hala, Diestel, Antje, Roessner, Albert, Schneider-Stock, Regine
Publicado em 2011

Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α

Por Abdel-Samad, Rana, Aouad, Patrick, Gali-Muhtasib, Hala, Sweidan, Zeinab, Hmadi, Raed, Kadara, Humam, D’Andrea, Egildo Luca, Fucci, Alessandra, Pisano, Claudio, Darwiche, Nadine
Publicado no Am J Cancer Res (2018)

Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models

Por Gali-Muhtasib, Hala, Ocker, Matthias, Kuester, Doerthe, Krueger, Sabine, El-Hajj, Zeina, Diestel, Antje, Evert, Matthias, El-Najjar, Nahed, Peters, Brigitte, Jurjus, Abdo, Roessner, Albert, Schneider-Stock, Regine
Publicado em 2008

Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

Por Ndreshkjana, Benardina, Çapci, Aysun, Klein, Volker, Chanvorachote, Pithi, Muenzner, Julienne K., Huebner, Kerstin, Steinmann, Sara, Erlenbach-Wuensch, Katharina, Geppert, Carol I., Agaimy, Abbas, Ballout, Farah, El-Baba, Chirine, Gali-Muhtasib, Hala, Roehe, Adriana Vial, Hartmann, Arndt, Tsogoeva, Svetlana B., Schneider-Stock, Regine
Publicado no Cell Death Dis (2019)