Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

Cancer stem cells (CSCs) residing in colorectal cancer tissues have tumorigenic capacity and contribute to chemotherapeutic resistance and disease relapse. It is well known that the survival of colorectal CSCs after 5-fluorouracil (5-FU)-based therapy leads to cancer recurrence. Thus CSCs represent...

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Publicado no:Cell Death Dis
Main Authors: Ndreshkjana, Benardina, Çapci, Aysun, Klein, Volker, Chanvorachote, Pithi, Muenzner, Julienne K., Huebner, Kerstin, Steinmann, Sara, Erlenbach-Wuensch, Katharina, Geppert, Carol I., Agaimy, Abbas, Ballout, Farah, El-Baba, Chirine, Gali-Muhtasib, Hala, Roehe, Adriana Vial, Hartmann, Arndt, Tsogoeva, Svetlana B., Schneider-Stock, Regine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522523/
https://ncbi.nlm.nih.gov/pubmed/31097715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1611-4
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