Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

Cancer stem cells (CSCs) residing in colorectal cancer tissues have tumorigenic capacity and contribute to chemotherapeutic resistance and disease relapse. It is well known that the survival of colorectal CSCs after 5-fluorouracil (5-FU)-based therapy leads to cancer recurrence. Thus CSCs represent...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Ndreshkjana, Benardina, Çapci, Aysun, Klein, Volker, Chanvorachote, Pithi, Muenzner, Julienne K., Huebner, Kerstin, Steinmann, Sara, Erlenbach-Wuensch, Katharina, Geppert, Carol I., Agaimy, Abbas, Ballout, Farah, El-Baba, Chirine, Gali-Muhtasib, Hala, Roehe, Adriana Vial, Hartmann, Arndt, Tsogoeva, Svetlana B., Schneider-Stock, Regine
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522523/
https://ncbi.nlm.nih.gov/pubmed/31097715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1611-4
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