Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells

PURPOSE: Enhancer of zeste homolog 2 (EZH2) is associated with epigenetic gene silencing and aggressiveness in many tumor types. However, the prognostic impact of high EZH2 expression is controversially discussed for colorectal cancer. For this reason, we immunohistochemically analyzed EZH2 expressi...

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Detalhes bibliográficos
Publicado no:J Cancer Res Clin Oncol
Main Authors: Böhm, Julian, Muenzner, Julienne Kathrin, Caliskan, Aylin, Ndreshkjana, Benardina, Erlenbach-Wünsch, Katharina, Merkel, Susanne, Croner, Roland, Rau, Tilman T., Geppert, Carol Immanuel, Hartmann, Arndt, Roehe, Adriana Vial, Schneider-Stock, Regine
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Original Article – Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708512/
https://ncbi.nlm.nih.gov/pubmed/31317325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-02977-1
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