Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells

PURPOSE: Enhancer of zeste homolog 2 (EZH2) is associated with epigenetic gene silencing and aggressiveness in many tumor types. However, the prognostic impact of high EZH2 expression is controversially discussed for colorectal cancer. For this reason, we immunohistochemically analyzed EZH2 expressi...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cancer Res Clin Oncol
Auteurs principaux: Böhm, Julian, Muenzner, Julienne Kathrin, Caliskan, Aylin, Ndreshkjana, Benardina, Erlenbach-Wünsch, Katharina, Merkel, Susanne, Croner, Roland, Rau, Tilman T., Geppert, Carol Immanuel, Hartmann, Arndt, Roehe, Adriana Vial, Schneider-Stock, Regine
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2019
Sujets:
Original Article – Cancer Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708512/
https://ncbi.nlm.nih.gov/pubmed/31317325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-02977-1
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