Loss of enhancer of zeste homologue 2 (EZH2) at tumor invasion front is correlated with higher aggressiveness in colorectal cancer cells

PURPOSE: Enhancer of zeste homolog 2 (EZH2) is associated with epigenetic gene silencing and aggressiveness in many tumor types. However, the prognostic impact of high EZH2 expression is controversially discussed for colorectal cancer. For this reason, we immunohistochemically analyzed EZH2 expressi...

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Bibliografske podrobnosti
izdano v:J Cancer Res Clin Oncol
Main Authors: Böhm, Julian, Muenzner, Julienne Kathrin, Caliskan, Aylin, Ndreshkjana, Benardina, Erlenbach-Wünsch, Katharina, Merkel, Susanne, Croner, Roland, Rau, Tilman T., Geppert, Carol Immanuel, Hartmann, Arndt, Roehe, Adriana Vial, Schneider-Stock, Regine
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2019
Teme:
Original Article – Cancer Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708512/
https://ncbi.nlm.nih.gov/pubmed/31317325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-02977-1
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