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Epigenetic Regulation of p21(cip1/waf1) in Human Cancer

p21(cip1/waf1) is a central regulator of cell cycle control and survival. While mutations are rare, it is commonly dysregulated in several human cancers due to epigenetic mechanisms influencing its transcriptional control. These mechanisms include promoter hypermethylation as well as additional path...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Ocker, Matthias, Al Bitar, Samar, Monteiro, Ana Carolina, Gali-Muhtasib, Hala, Schneider-Stock, Regine
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769618/
https://ncbi.nlm.nih.gov/pubmed/31514410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091343
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