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Interferon Regulatory Factor 1 (IRF-1) Induces p21(WAF1/CIP1) Dependent Cell Cycle Arrest and p21(WAF1/CIP1) Independent Modulation of Survivin in Cancer Cells
We have shown that the ectopic expression of Interferon Regulatory Factor (IRF-1) results in human cancer cell death accompanied by the down-regulation of the Inhibitor of Apoptosis Protein (IAP) survivin and the induction of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1). In this report, we i...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304016/ https://ncbi.nlm.nih.gov/pubmed/22200613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.12.027 |
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