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A human ribonuclease induces apoptosis associated with p21(WAF1/CIP1 )induction and JNK inactivation
BACKGROUND: Ribonucleases are promising agents for use in anticancer therapy. Among the different ribonucleases described to be cytotoxic, a paradigmatic example is onconase which manifests cytotoxic and cytostatic effects, presents synergism with several kinds of anticancer drugs and is currently i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025972/ https://ncbi.nlm.nih.gov/pubmed/21223552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-9 |
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