An in vitro evolved glmS ribozyme has the wildtype fold but loses coenzyme dependence

Eitemau Tebyg

• In vitro evolution of coenzyme-independent variants from the glmS ribozyme structural scaffold
  gan: Lau, Matthew W.L., et al.
  Cyhoeddwyd: (2016)
• The glmS ribozyme: use of a small molecule coenzyme by a gene-regulatory RNA
  gan: Ferré-D’Amaré, Adrian R.
  Cyhoeddwyd: (2010)
• Use of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small molecules
  gan: Ferré-D'Amaré, Adrian R.
  Cyhoeddwyd: (2011)
• The glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphate
  gan: Gong, Bo, et al.
  Cyhoeddwyd: (2011)
• Glucosamine and Glucosamine-6-phosphate Derivatives: Catalytic Cofactor Analogs for the glmS Ribozyme
  gan: Posakony, Jeffrey J., et al.
  Cyhoeddwyd: (2013)