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Glucosamine and Glucosamine-6-phosphate Derivatives: Catalytic Cofactor Analogs for the glmS Ribozyme

Two analogues of glucosamine-6-phosphate (GlcN6P, 1) and five of glucosamine (GlcN, 2) were prepared for evaluation as catalytic cofactor of the glmS ribozyme, a bacterial gene-regulatory RNA that controls cell wall biosynthesis. Glucosamine and allosamine with 3-azido substitutions were prepared by...

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Bibliographic Details
Main Authors: Posakony, Jeffrey J., Ferré-D'Amaré, Adrian R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728379/
https://ncbi.nlm.nih.gov/pubmed/23578404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo400192e
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