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Use of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small molecules

The glmS ribozyme-riboswitch is the first known example of a naturally occurring catalytic RNA that employs a small molecule as a coenzyme. Binding of glucosamine-6-phosphate (GlcN6P) activates self-cleavage of the bacterial ribozyme, which is part of the mRNA encoding the metabolic enzyme GlcN6P-sy...

詳細記述

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書誌詳細
第一著者: Ferré-D'Amaré, Adrian R.
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158913/
https://ncbi.nlm.nih.gov/pubmed/21930586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0131
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