TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance

Regulatory B cells (Bregs) have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined anti-TIM-1 and anti-CD45RB antibody treatment results in tolerance to full MHC-mismatched islet allografts in mice by generating Bregs that...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Kang Mi, Stott, Ryan T, Zhao, Gaoping, SooHoo, Julie, Xiong, Wei, Lian, Moh Moh, Fitzgerald, Lindsey, Shi, Shuai, Akrawi, Elsie, Lei, Ji, Deng, Shaoping, Yeh, Heidi, Markmann, James F, Kim, James I
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048633/
https://ncbi.nlm.nih.gov/pubmed/24700192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344062
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