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TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance
Regulatory B cells (Bregs) have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined anti-TIM-1 and anti-CD45RB antibody treatment results in tolerance to full MHC-mismatched islet allografts in mice by generating Bregs that...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048633/ https://ncbi.nlm.nih.gov/pubmed/24700192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344062 |
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