TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance

Regulatory B cells (Bregs) have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined anti-TIM-1 and anti-CD45RB antibody treatment results in tolerance to full MHC-mismatched islet allografts in mice by generating Bregs that...

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Bibliografske podrobnosti
Main Authors: Lee, Kang Mi, Stott, Ryan T, Zhao, Gaoping, SooHoo, Julie, Xiong, Wei, Lian, Moh Moh, Fitzgerald, Lindsey, Shi, Shuai, Akrawi, Elsie, Lei, Ji, Deng, Shaoping, Yeh, Heidi, Markmann, James F, Kim, James I
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048633/
https://ncbi.nlm.nih.gov/pubmed/24700192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344062
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