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Elevated Levels of Interferon-γ Production by Memory T Cells Do Not Promote Transplant Tolerance Resistance in Aged Recipients

Immunosenescence predisposes the elderly to infectious and autoimmune diseases and impairs the response to vaccination. We recently demonstrated that ageing also impedes development of transplantation tolerance. Unlike their young counterparts (8-12 weeks of age) aged male recipients (greater than 1...

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Bibliografische gegevens
Hoofdauteurs: Kim, James I., Stott, Ryan T., Soohoo, Julie, Lee, Kang Mi, Zhao, Gaoping, Yeh, Heidi, Deng, Shaoping, Markmann, James F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858330/
https://ncbi.nlm.nih.gov/pubmed/24340063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082856
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