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Generation of Adaptive Regulatory T Cells by Alloantigen Is Required for Some But Not All Transplant Tolerance Protocols
BACKGROUND: Because CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) are essential for the maintenance of self-tolerance, significant interest surrounds the developmental cues for thymic-derived natural Tregs (nTregs) and periphery-generated adaptive Tregs (aTregs). In the transplant setting, the al...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727173/ https://ncbi.nlm.nih.gov/pubmed/21386770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31820e50b3 |
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