Generation of Adaptive Regulatory T Cells by Alloantigen Is Required for Some But Not All Transplant Tolerance Protocols

BACKGROUND: Because CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) are essential for the maintenance of self-tolerance, significant interest surrounds the developmental cues for thymic-derived natural Tregs (nTregs) and periphery-generated adaptive Tregs (aTregs). In the transplant setting, the al...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kim, James I., O’Connor, Matthew R., Duff, Patrick E., Zhao, Gaoping, Lee, Kang Mi, Eliades, Philip, Deng, Shaoping, Yeh, Heidi, Caton, Andrew J., Markmann, James F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727173/
https://ncbi.nlm.nih.gov/pubmed/21386770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31820e50b3
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi