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TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance

Regulatory B cells (Bregs) have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined anti-TIM-1 and anti-CD45RB antibody treatment results in tolerance to full MHC-mismatched islet allografts in mice by generating Bregs that...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Lee, Kang Mi, Stott, Ryan T, Zhao, Gaoping, SooHoo, Julie, Xiong, Wei, Lian, Moh Moh, Fitzgerald, Lindsey, Shi, Shuai, Akrawi, Elsie, Lei, Ji, Deng, Shaoping, Yeh, Heidi, Markmann, James F, Kim, James I
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048633/
https://ncbi.nlm.nih.gov/pubmed/24700192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344062
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