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Protons and Psalmotoxin-1 reveal nonproton ligand stimulatory sites in chicken acid-sensing ion channel: Implication for simultaneous modulation in ASICs

Acid-sensing ion channels (ASICs) are proton-sensitive, sodium-selective channels expressed in the nervous system that sense changes in extracellular pH. These ion channels are sensitive to an increasing number of nonproton ligands that include natural venom peptides and guanidine compounds. In the...

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Bibliografski detalji
Glavni autori: Smith, Rachel N, Gonzales, Eric B
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048342/
https://ncbi.nlm.nih.gov/pubmed/24262969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.26978
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