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Nonproton Ligand Sensing Domain Is Required for Paradoxical Stimulation of Acid-sensing Ion Channel 3 (ASIC3) Channels by Amiloride
Acid-sensing ion channels (ASICs), which belong to the epithelial sodium channel/degenerin family, are activated by extracellular protons and are inhibited by amiloride (AMI), an important pharmacological tool for studying all known members of epithelial sodium channel/degenerin. In this study, we r...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234944/ https://ncbi.nlm.nih.gov/pubmed/21998313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289058 |
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