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Nonproton Ligand Sensing Domain Is Required for Paradoxical Stimulation of Acid-sensing Ion Channel 3 (ASIC3) Channels by Amiloride

Acid-sensing ion channels (ASICs), which belong to the epithelial sodium channel/degenerin family, are activated by extracellular protons and are inhibited by amiloride (AMI), an important pharmacological tool for studying all known members of epithelial sodium channel/degenerin. In this study, we r...

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מידע ביבליוגרפי
Main Authors: Li, Wei-Guang, Yu, Ye, Huang, Chen, Cao, Hui, Xu, Tian-Le
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234944/
https://ncbi.nlm.nih.gov/pubmed/21998313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289058
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