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ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain

BACKGROUND: Acid-sensing ion channels (ASICs) have long been known to sense extracellular protons and contribute to sensory perception. Peripheral ASIC3 channels represent natural sensors of acidic and inflammatory pain. We recently reported the use of a synthetic compound, 2-guanidine-4-methylquina...

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Autors principals: Li, Wei-Guang, Yu, Ye, Zhang, Zhu-Dan, Cao, Hui, Xu, Tian-Le
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017031/
https://ncbi.nlm.nih.gov/pubmed/21143836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-88
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