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ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain

BACKGROUND: Acid-sensing ion channels (ASICs) have long been known to sense extracellular protons and contribute to sensory perception. Peripheral ASIC3 channels represent natural sensors of acidic and inflammatory pain. We recently reported the use of a synthetic compound, 2-guanidine-4-methylquina...

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Detalhes bibliográficos
Main Authors: Li, Wei-Guang, Yu, Ye, Zhang, Zhu-Dan, Cao, Hui, Xu, Tian-Le
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017031/
https://ncbi.nlm.nih.gov/pubmed/21143836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-88
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