Atomic Level Characterization of the Nonproton Ligand-sensing Domain of ASIC3 Channels

Acid-sensing ion channels (ASICs) are known to be primarily activated by extracellular protons. Recently, we characterized a novel nonproton ligand (2-guanidine-4-methylquinazoline, GMQ), which activates the ASIC3 channel subtype at neutral pH. Using an interactive computational-experimental approac...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Yu, Ye, Li, Wei-Guang, Chen, Zhi, Cao, Hui, Yang, Huaiyu, Jiang, Hualiang, Xu, Tian-Le
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137073/
https://ncbi.nlm.nih.gov/pubmed/21586569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239558
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares