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In vivo Targeting of Adoptively Transferred T-cells with Antibody- and Cytokine-Conjugated Liposomes
In adoptive cell therapy (ACT), autologous tumor-specific T-cells isolated from cancer patients are activated and expanded ex vivo, then infused back into the individual to eliminate metastatic tumors. A major limitation of this promising approach is the rapid loss of ACT T-cell effector function in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046900/ https://ncbi.nlm.nih.gov/pubmed/23770010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.05.037 |
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