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Cytokine Binding by Polysaccharide-Antibody Conjugates

Cytokine-neutralizing antibodies are used in treating a broad range of inflammatory conditions. We demonstrate that monoclonal antibodies against interleukin-1β and tumor necrosis factor-α were still active when conjugated to high molecular weight polysaccharides. These polysaccharides are hydrophil...

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Hlavní autoři: Sun, Liang Tso, Bucholz, Kyle, Lotze, Michael T., Washburn, Newell R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008761/
https://ncbi.nlm.nih.gov/pubmed/20726535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100150z
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