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Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles
Regulating molecular interactions in the T-cell synapse to prevent autoimmunity or, conversely, to boost anti-tumor immunity has long been a goal in immunotherapy. However, delivering therapeutically meaningful doses of immune-modulating compounds into the synapse represents a major challenge. Here,...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395588/ https://ncbi.nlm.nih.gov/pubmed/22594972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.04.029 |
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