The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice

BACKGROUND: The deposition of the amyloid β-peptide (Aβ) in the brain is one of the hallmarks of Alzheimer’s disease (AD). It is not yet clear whether Aβ always leads to similar changes or whether it induces different features of neurodegeneration in relation to its intra- and/or extracellular local...

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Main Authors: Rijal Upadhaya, Ajeet, Scheibe, Frederik, Kosterin, Irina, Abramowski, Dorothee, Gerth, Janina, Kumar, Sathish, Liebau, Stefan, Yamaguchi, Haruyasu, Walter, Jochen, Staufenbiel, Matthias, Thal, Dietmar Rudolf
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046770/
https://ncbi.nlm.nih.gov/pubmed/24252227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-77
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